Fig. 2. Effect of LINS01005 and LINS01007 on the bronchoalveolar lavage (BALF) cells and IgE serum levels. Balb/c were immunized with an i.p. injection of ovalbumin/alumen, one booster injection 7 days later, and two ovalbumin aerosol challenges (2,5%, 20 min) on days 14 and 21 post immunization. Histamine receptor antagonists were given i.p. 30 min before each aerosol challenge. BALF and serum were performed 24h after the second challenge. Total cells (A and B), eosinophils BALF cells (C and D), total IgE (E) and OVA-Specific IgE serum levels (F). Results are the mean ± S.E.M. of 8 animals/group. ** P< 0.01 in comparison with the control group and ## P< 0.01 in comparison with the asthma group.